Table 5.

mRNA levels of vascular markers in aortae of 6-mo-old mice

	Cc1+/+	Ccl−/−
Ang-1	0.98 ± 0.24	0.25 ± 0.01*
Ang-2	0.37 ± 0.05	0.10 ± 0.02†
VEGF-A	9.53 ± 1.38	3.40 ± 0.41†
VEGF-C	0.14 ± 0.02	0.10 ± 0.01
VEGF-D	0.62 ± 0.08	0.72 ± 0.10
VEGFR-1	1.91 ± 0.22	0.60 ± 0.10‡
VEGFR-2	1.31 ± 0.13	0.50 ± 0.06‡
β-Catenin	8.22 ± 0.73	4.83 ± 0.36†

Values are expressed as means ± SE. Ang, angiopoietin; VEGF, vascular endothelial growth factor. Aortic arch was isolated from 6-mo-old male mice (n ≥ 6) to measure mRNA content by qRT-PCR (normalized to Gapdh).

^*P < 0.01,

^†P < 0.001,

^‡P < 0.0001 vs. Cc1^+/+.