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A: representative Western blot of nuclear Nrf2 protein content. Means ± SE values of cardiac nuclear factor erythroid 2-related factor 2 (Nrf2) mRNA expression (B), nuclear Nrf2 protein expression (C), and Nrf2 activity (D) from LETO, OLETF, and OLETF + ARB rats. *Significant difference from LETO (P < 0.05). †Significant difference from OLETF (P < 0.05).
