Table 2.
Effect of shear patterns on the mRNA expression of KCa subtypes in HCAECs
| Shear Pattern | KCa1.1 | KCa2.1 | KCa2.2 | KCa2.3 | KCa3.1 |
|---|---|---|---|---|---|
| LS | 9.5 ± 2.4 (n = 8)* | 0.3 ± 0.1 (n = 8)* | 0.3 ± 0.1 (n = 8)* | 3.2 ± 0.4 (n = 25)*,† | 44.7 ± 9.7 (n = 30)*,† |
| OS | 6.0 ± 2.7 (n = 5) | 0.2 ± 0.1 (n = 5)* | 0.3 ± 0.1 (n = 5)* | 1.0 ± 0.2 (n = 8) | 2.1 ± 0.4 (n = 9)* |
Values are means ± SE, and indicate the fold change of mRNA expression of each KCa subtype compared to the static (ST) condition [2ΔCT(X) − ΔCT(static)]. OS, oscillatory shear stress.
*
Significant difference vs. ST (P < 0.05).
†
Significant difference vs. OS (P < 0.05).