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. 2013 Jun 14;305(4):H477–H483. doi: 10.1152/ajpheart.00914.2012

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Fig. 4. — Apoptotic cardiomyocytes in the infarct zone. Immunohistochemical images of TUNEL⁺ cardiomyocyte nuclei in wild-type (WT) and mPer-M I/R and IPC hearts (×400). The percentage of TUNEL⁺ cardiomyocyte nuclei decreased 54% in C57 IPC hearts compared with C57 I/R hearts (P < 0.001). mPer2-M IPC hearts had 46% less apoptotic cardiomyocytes than C57 IPC hearts (‡P < 0.05). The no. of apoptotic cardiomyocyte nuclei in mPer2-M I/R hearts was 57% less than C57 I/R hearts (†P < 0.001) and 42% less in mPer2-M IPC hearts compared with mPer2-M I/R hearts (#P < 0.05), but there was no difference in the no. of TUNEL⁺ cardiomyocytes in mPer2-M I/R hearts compared with C57 IPC hearts.