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Effect of benzamil in the presence of endothelin-1 (ET-1) on Na reabsorption, JNa, in the CCD of male mice. In the presence of ET-1, benzamil did not significantly inhibit Na reabsorption (ET-1 26.8 ± 7.2 vs. ET-1 + benzamil 12.5 ± 3.2, P = 0.12, n = 6). Extended line connects the means ± SE for the 2 experimental periods.
