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. 2013 Dec 2;5(1):40–53. doi: 10.1364/BOE.5.000040

Fig. 3.

Fig. 3

Inverse model of diffuse reflectance. First, an initial guess for the tissue parameters is used to generate a spectrum with the forward model. Next, the error between the measured and modeled spectra is calculated and the parameters are updated using an optimization routine that minimizes the error between the modeled and measured spectra.