Figure 4. The 3-NP-treated mice show evidence for hyperactivity during sleep phase.

Open-field test was performed during the animals normal sleep time (ZT 2–6) in saline-injected control mice (n=7) and 3-NP-treated mice (n=7). * indicates P<0.05 as measured by a Mann–Whitney U test. There were no significant differences in other parameters measured such as vertical or stereotyped movements between groups.