Table 1.
Morphometric characteristics and baseline hemodynamics.
| Variable | Control | PPH | Diet | Treatment | Interaction | ||
|---|---|---|---|---|---|---|---|
| Ethanol | Enalapril | Ethanol | Enalapril | ||||
| (n=10) | (n=10) | (n=8) | (n=10) | ||||
| Body weight (g) | 438 ± 16 | 427 ± 16 | 366 ± 20 | 349 ± 17 | P<0.0001 | P=0.4140 | P=0.8799 |
| Heart weight/body weight (mg g−1) | 2.70 ± 0.04 | 2.52 ± 0.06 | 2.70 ± 0.04 | 2.62 ± 0.07 | P=0.3982 | P=0.0269 | P=0.3108 |
| Heart weight/tibial length (mg mm−1) | 28.7 ± 0.7 | 25.9 ± 1.0 | 25.1 ± 0.8 | 23.0 ± 0.8 | P=0.0007 | P=0.0074 | P=0.6892 |
| Under anesthesia | (n=10) | (n=10) | (n=8) | (n=10) | |||
| MAP(mmHg) | 88 ± 5 | 97 ± 5 | 92 ± 6 | 82 ± 6 | P=0.3197 | P=0.8975 | P=0.0874 |
| HR (beats min−1) | 346 ± 5 | 362 ± 8 | 346 ± 9 | 356 ± 9 | P=0.7097 | P=0.0961 | P=0.7124 |
| Baseline signal to noise ratio for RSNA | 4.1 ± 0.9 | 5.0 ± 0.8 | 3.8 ± 0.9 | 4.1 ± 0.5 | P=0.4267 | P=0.4630 | P=0.7626 |
| After decerebration | (n=10) | (n=10) | (n=8) | (n=10) | |||
| MAP(mmHg) | 93 ± 7 | 74 ± 4 | 84 ± 5 | 65 ± 4 | P=0.0855 | P=0.0008 | P=0.9691 |
| HR (beats min−1) | 410 ± 18 | 430 ± 12 | 388 ± 10 | 407 ± 15 | P=0.1290 | P=0.1776 | P=0.9749 |
| Baseline signal to noise ratio for RSNA | 6.6 ± 1.1 | 5.7 ± 1.2 | 5.4 ± 1.2 | 6.7 ± 1.2 | P=0.9271 | P=0.8519 | P=0.3918 |
Values are means ± S.E.M.