Table 1.
Demographic and clinical characteristics of children with urticaria and healthy children.
| Acute urticaria—single episode | Recurrent urticaria | Healthy children | |
|---|---|---|---|
| Number | 39 | 17 | 41 |
| Age (y.) | 8.56 ± 1.67 | 9.61 ± 2.45 | 9.36 ± 1.57 |
| M/F | 16/23 | 7/10 | 17/24 |
| CRP (mg/L) | 11.99 ± 7.67* | 7.44 ± 8.08** | 1.05 ± 0.59 |
| WBC (109/L) | 9.44 ± 1.21 | 8.19 ± 1.74 | 7.3 ± 1.54 |
| D-dimer | 1.23 ± 0.71# | 0.85 ± 0.81## | nd |
| E % (absolute count, cells/µL) | 1.94 ± 1.94 (236.87 ± 158.7) | 1.47 ± 0.95 (136.14 ± 18.13) | 1.9 ± 0.96 (177.3 ± 60) |
| IgE (kU/L) | 225.79 ± 102.6 | 102.82 ± 75.79 | 72 ± 47.17 |
| IgA (g/L) | 1.22 ± 0.17 | 1.20 ± 0.17 | 1.13 ± 0.31 |
| IgM (g/L) | 1.04 ± 0.09 | 0.94 ± 0.08 | 0.99 ± 0.21 |
| IgG (g/L) | 8.53 ± 0.59 | 8.54 ± 0.66 | 8.63 ± 0.98 |
| Personal allergic disease | 9 | 5 | |
| Family allergic disease | 5 | 8 | |
| Symptoms suggestive of infection | 21 | 5 | |
| UAS 1/2/3& | 12/10/17 | 11/3/3 |
Data are shown as mean ± standard error. P values from Mann-Whitney U test.
*Children with single episode of acute urticaria versus control group P < 0.00001.
**Children with recurrent urticaria versus control group P < 0.007.
# n = 22, ## n = 15.
&Urticaria activity score: 1 mild urticaria (0–3), 2 moderate urticaria (3-4), and 3 severe urticaria (5-6).