Table 1. Summary of miR loci transposable element origins.
Repeat type | Sequence based alignment | Familial inclusion | Total MiRs 2013 | Total MiRs 2011 | Total # of MiRs |
---|---|---|---|---|---|
DNA transposon | 467 | 50 | 517 | 891 | 1408 |
LTR retrotransposon | 235 | 1 | 236 | 414 | 650 |
Non-LTR retrotransposon | 305 | 2 | 307 | 814 | 1121 |
-LINE | 186 | 1 | 187 | 461 | 648 |
-SINE | 119 | 1 | 120 | 353 | 473 |
Noncoding RNAs | 128 | 0 | 128 | 61 | 189 |
tRNAs | 33 | 0 | 33 | 51 | 84 |
Satellites | 6 | 3 | 9 | 137 | 146 |
Other | 39 | 1 | 40 | 24 | 64 |
Total | 1156 | 57 | 1213 | 2392 | 3605 |
Repeat Type, RepBase classification.22 Sequence Based Alignment, total number of unique miR origins identified through alignment to a consensus transposable element. Familial Inclusion, total number of unique miR origins determined through familial inclusion. Total MiRs 2013, total origins determined through both sequence based alignment and familial inclusion in the current study. Total MiRs 2011, total origins determined through both sequence based alignment and familial inclusion in our initial analysis.24 Total # of MiRs, total origins determined through both sequence based alignment and familial inclusion in both the current analysis and 2011 study. Others, miRs significantly aligning to characterized RNA structural elements (e.g., IRES elements) contained within the RFAM data set.35,36