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Serum from rats dosed with 30, 45 or 60/kg of anti-Her2 Cys-ADC or 30, 60 or 90 mg/kg of anti-Her2 position 1-ADC were collected and the total amount of antibody (TAb) or ADC was measured via ELISA. (A) The pharmacokinetic profile of the anti-Her2 Cys-ADC was evaluated. (B) The pharmacokinetic profile of the anti-Her2 position 1-ADC was evaluated.
