Table 1. Summary for seven genes recruited to the secretory proteome of the submandibular salivary gland in the little brown bat, Myotis lucifugus.
Gene | Protein | FPKM value (mRNA) | Pathway | Typical Expression Sites | Lipid-associated Function(s) |
RETNLB | Resistin-like β | 355.6 | Endocrine | Intestinal epithelium (restricted) | Lipidemia and insulin resistance |
LCN2 | Lipocalin 2 | 353.4 | Endocrine | Liver and adipose cells | Lipid transport |
C3 | Complement 3 | 191.4 | Endocrine | Liver and adipose cells | Lipidemia, lipid transport |
PSAP | Prosaposin | 139.9 | Endocrine | Kidney tubules, mammary glands | Lipid transport |
CLU | Clusterin | 60.9 | Endocrine | Intestine, pancreas, liver | Lipid transport |
APOE | Apolipoprotein E | 35.1 | Endocrine | Liver, adipose cells, macrophages | Lipid transport |
CEL | Carboxyl ester lipase | 30.2 | Exocrine | Pancreas, lactating mammary gland | Lipid hydrolysis |
The predicted secretory pathway (exocrine or endocrine) is based on protein function. Expression sites selected as typical are based on a combination of literature and EST profile.