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. 2013 Aug 6;8(10):1013–1022. doi: 10.4161/epi.25927

graphic file with name epi-8-1013-g2.jpg

Figure 2. Schematic representation of promoter CpG island hypermethylation in cancer. Filled and unfilled lollypops represent methylated and unmethylated CpGs, respectively. HAT, histone acetyltransferase; Pol II, DNA polymerase II; DNMT, DNA methyl transferase; HDAC, histone deacetylase; PcG, polycomb group proteins.