Table 3B. LeTx neutralizing antibody titers in rabbits immunized with pp-PA83 plus Alhydrogel.
| pp-PA83 dose | 135 µg | 67.5 µg | 22.5 µg | 7.5 µg | 0 µg | |
|---|---|---|---|---|---|---|
| 0.1% Alhydrogel | 0.5 mg/mL | 0.5 mg/mL | 0.5 mg/mL | 0.5 mg/mL | 0.5 mg/mL | |
| aluminum | aluminum | aluminum | aluminum | aluminum | ||
| GMT | Day 21 | 28 ± 19 | 13 ± 5 | 10 ± 0 | 17 ± 6 | 17 ± 6 |
| ED50 ± SE | Day 35 | 525 ± 526 | 719 ± 224 | 208 ± 407 | 46 ± 117 | 10 ± 0 |
| Day 56 | 1688 ± 768 | 867 ± 107 | 743 ± 337 | 758 ± 247 | 10 ± 0 | |
| % Responders | 100% | 100% | 100% | 100% | 0% | |
| (Day 56) | ||||||
GMT: Geometric mean titer. ED50: Effective dilution 50. SE: Standard error.