Table 4B. LeTx neutralizing antibody titers in rabbits immunized with pp-PA83 plus Alhydrogel prior to challenge.
| pp-PA83 | 135 µg | 67.5 µg | 22.5 µg | 7.5 µg | 0 µg | |
|---|---|---|---|---|---|---|
| 0.1% Alhydrogel | 0.5 mg/mL aluminum |
0.5 mg/mL aluminum |
0.5 mg/mL aluminum |
0.5 mg/mL aluminum |
0.5 mg/mL aluminum |
|
|
GMT ED50 ± SE |
Day 20 | 19 ± 13 | 10 ± 0 | 18 ± 13 | 11 ± 1 | 13 ± 3 |
| Day 41 | 351 ± 100 | 154 ± 66 | 78 ± 149 | 20 ± 26 | 10 ± 0 | |
|
% Responders (Day 41) |
88% | 88% | 38% | 13% | 0% | |
GMT: Geometric mean titer. ED50: Effective dilution 50. SE: Standard error.