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Figure 4. Induction of humoral immune responses against SIVgag. hCD46tg mice were given 0 or 500 mIU MV-nAb prior to i.m. or i.n. immunization with 1 × 105 pfu rMVSIVgag. Samples were collected at 4 weeks post prime i.m. (panel A) or i.n. (panel B) and 4 weeks post i.m. boost with 1 × 105 pfu rMV-SIVgag. The median values are shown as lines.
