. 2013 Sep 12;3(1):e25698. doi: 10.4161/cl.25698

Table 1. Distinguishing properties of low, high, and very high [PIN⁺] variants.

	Distinguishing characteristics of [PIN⁺] variants	Low [PIN⁺]	High [PIN⁺]	Very high [PIN⁺]
Effects on [PSI⁺]	Efficiency of [PSI⁺] induction	+	+++	++++
	Predominant [PSI⁺] variant induced in vivo at 30 °C	weak	weak	strong
	Predominant [PSI⁺] variant induced in vivo at 4 °C	Not tested	strong	Not tested
Other features	Level of soluble Rnq1	++	+	+++
	Single (s.d.) or multi (m.d.) fluorescent Rnq1:Gfp dots	s.d.	m.d.	s.d.
	Average [PIN⁺] seed (propagon) number/cell	25 ± 5	96 ± 17	50 ± 5
	Oligomers break into sub-particles at 60 °C¹²	no	yes	no

Table 1. Distinguishing properties of low, high, and very high [PIN+] variants.