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. 2014 Jan 14;9(1):e85144. doi: 10.1371/journal.pone.0085144

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© 2014 Yi et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Collagen contents were determined by Western blot analysis. Left panel: Typical examples of Western blot bands showing upregulation of both collagen I and collagen III; right panel: averaged band densities, normalized to β-actin. Note that the collagen contents were substantially higher in atrial tissues from AF patients than from SR controls. SR, sinus rhythm; AF, atrial fibrillation. *P<0.05; n = 10.