Figure 2A. Inhibition of ATP-dependent transport of [3H]-paclitaxel in placental IOV by pravastatin.
Pravastatin inhibited ATP-dependent uptake of paclitaxel (40 nM) with the IC50 values of 11 μM. Each point represents the mean ± S.D. from 3 experiments in duplicate.
Figure 2B. Inhibition of ATP-dependent transport of [3H]-estrone sulfate in placental IOV by pravastatin.
Pravastatin inhibited ATP-dependent uptake of estrone sulfate (100 nM) with the IC50 values of 30 μM. Each point represents the mean ± S.D. from 3 experiments in duplicate.