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Effect of Rspo1 and Rspo3 on food intake. A and B, Dark phase and 24-hour food intake after third ventricular injection of Rspo1. n = 8; *, P < .05. C and D, Dark phase and 24-hour food intake after third ventricle injection of Rspo3. n = 8; *, P < .05. E, Taste aversion test after third ventricular injection of Rspo1. n = 8; *, P < .05.
