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. 2014 Jan 15;34(3):764–775. doi: 10.1523/JNEUROSCI.3112-13.2014

Figure 4.

Figure 4.

Functional properties of wild-type and V495A CLH-3b coexpressed with either functional or kinase dead (KD) GCK-3. A, Representative current traces. B, C, Current-to-voltage relationships. *p < 0.001 and **p < 0.01 compared with channels coexpressed with KD GCK-3. Statistical analyses were performed only at voltages more hyperpolarized than the activation voltage of channels coexpressed with GCK-3. D, Activation voltages. *p < 0.001 compared with wild-type CLH-3b coexpressed with KD GCK-3; **p < 0.0001 compared with channels expressed with KD GCK-3. E, The 50% rise times, defined as the time required for whole-cell current to reach 50% activation when membrane voltage is stepped from 0 mV to −100 mV for 1 s. *p < 0.001 compared with channels coexpressed with KD GCK-3; **p < 0.00001 compared with wild-type channels coexpressed with GCK-3. Values shown in B–E are means ± SE. n = 4–6.