Figure 5.

Extrapolation and distributions of population model parameters from electrophysiology data. Details are described in Materials and Methods. The gray dots corresponds to N = 2000 samples generated from the joint distribution used for the simulation study. a, Mean IBI μ to SD σ regression and distribution fitting. Blue circles correspond to the 28 data points. The red dotted lines correspond to the sigmoid-scaled SD around the fitted line. b, Mean IBI μ to the location parameter of the sigmoid x₀ regression and distribution fitting. Blue circles correspond to the 15 data points. The red dotted lines correspond to the sigmoid-scaled SD around the fitted line. c, x₀ to the slope of sigmoid b regression and distribution fitting. Blue circles correspond to the 15 data points. Blue solid line is the fitted exponential curve.