Basal IL-6 expression and IL-6 induced STAT3 phosphorylation in the OFC. a, The majority of IL-6-positive cells in the OFC also expressed the neuronal marker, NeuN. b, A smaller percentage of IL-6-positive cells also expressed the astrocytic marker, GFAP. c, IL-6 expression was not observed in CD11b-positive microglia. d, The majority of phospho-STAT3-positive cells in the OFC also expressed the neuronal marker, NeuN. e, In addition, astrocytes labeled with GFAP expressed phospho-STAT3. f, A very small number of Iba1-positive microglia were observed to express phospho-STAT3 in the OFC. Scale bar, 10 μm. n = 3 per group.