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Comparison of vasodilation-congestion (A) hemorrhage (B) polymorphonuclear (PMN) leukocyte infiltration (C) mononuclear leukocyte (MNL) infiltration (D) alveolar wall thickening (E) alveolar destruction-emphysematous appearance (F) and focal organization between Group II (LPS-only) and Group V (100 mg/kg bosentan). *p = 0.0001 for A, B, D, E and F, p = 0.002 for C, and p = 0.001 for G.
