Table 5.
Number needed to screen to identify one cardiovascular event excess per year according to different estimated prevalence of significant CADa
| Prevalence of CAD ≥70% estimated by the risk score | Number of patients with CAD ≥70% | Number of patients with CAD <70% | Number of events in patients with CAD ≥70% (AR = 13%) | Number of events in patients with CAD <70% (AR = 2%) | Excess of events in patients with CAD ≥70% | Number needed to screen to identify one cardiovascular event |
|---|---|---|---|---|---|---|
| 5% |
5 |
95 |
0.65 |
1.90 |
−1.25 |
N/A |
| 10% |
10 |
90 |
1.30 |
1.80 |
−0.50 |
N/A |
| 15% |
15 |
85 |
1.95 |
1.70 |
0.25 |
400 |
| 20% |
20 |
80 |
2.60 |
1.60 |
1.00 |
100 |
| 25% |
25 |
75 |
3.25 |
1.50 |
1.75 |
57 |
| 30% |
30 |
70 |
3.90 |
1.40 |
2.50 |
40 |
| 35% |
35 |
65 |
4.55 |
1.30 |
3.25 |
31 |
| 40% | 40 | 60 | 5.20 | 1.20 | 4.00 | 25 |
aBased on 100 coronary angiographies. CAD, coronary artery disease; N/A, not applicable; AR, absolute risk.