Table 2.
Selection of SNPs
| No. | SNP marker | Source a | Included b | Location | Allele |
|---|---|---|---|---|---|
| SNP 1 |
rs4969239 |
Tag SNP |
Y |
Intron 1 |
A/G |
| SNP 2 |
rs4969358 |
Tag SNP |
Y |
Intron 1 |
A/C |
| SNP 3 |
rs6565531 |
Tag SNP |
Y |
Intron 1 |
A/G |
| SNP 4 |
rs8079626 |
Tag SNP |
Y |
Intron 1 |
A/G |
| SNP 5 |
rs3934492 |
Tag SNP |
Y |
Intron 3 |
C/G |
| SNP 6 |
rs9901648 |
Tag SNP |
Y |
Intron 3 |
A/G |
| SNP 7 |
rs4076037 |
Tag SNP |
Y |
Intron 3 |
A/G |
| SNP 8 |
rs8066330 |
Tag SNP |
Y |
Intron 3 |
C/T |
| SNP 9 |
rs4969385 |
reported |
Y |
Intron 6 |
C/T |
| |
rs8067235 |
Tag SNP |
N, located on the same block with rs6565531(D’ = 1, r
2
= 0.642) |
||
| rs6565532 |
Tag SNP |
N, located on the same block with rs6565531 (D’ = 1, r
2
= 0.798) |
|||
| rs8070741 |
Tag SNP |
N, with moderate LD with rs9901648 (D’ = 0.896, r
2
= 0.803) |
|||
| rs11657997 |
Tag SNP |
N, with moderate LD with rs9901648 (D’ = 1, r
2
= 0.783) |
|||
| rs4969355 | Tag SNP | N, located on the same block with rs4969239 (D’ = 1, r 2 = 0.764) and rs4969359 (D’ = 1,r 2 = 0.783) | |||
Abbreviation:LD linkage disequilibrium.
atag SNP, pick up using Haploview based on the CHB database from Hapmap, with an r 2 threshold of 0.80 from all SNPs with minor alleles frequency (MAF) > 0.25; reported, which has been studied and shown potential association with adult ADHD in Spanish population [16].
bY, included for further genotyping and analyses; N, not included for further genotyping.