Table 2.
Geometric mean and percent control of fleas recovered in premises flea traps in naturally infested homes when dogs and cats were treated with indoxacarb or fipronil (s)-methoprene based topical spot-on formulations
|
Treatment group |
# homes completing study |
|
Days post-treatment
1
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| Day 0 | Day 7 | Day 14 | Day 21 | Day 28 – 30 | Day 40 - 45 | Day 54 – 60 | |||
| Indoxacarb2 |
18 |
Geomean4 |
29.4a |
8.1a |
5.2a |
3.8a |
3.5a |
0.9a |
0.7a |
| |
% control5 |
|
72.4 |
82.4 |
87.2 |
87.9 |
97.0 |
97.7 |
|
| Fipronil (s)-methoprene3 |
19 |
Geomean |
25.5a |
9.5a |
7.5a |
7.0a |
10.1a |
5.1b |
3.9b |
| % control | 62.6 | 70.4 | 72.4 | 60.3 | 79.9 | 84.6 | |||
1Dogs and cats treated on day 0 and again between days 28 – 30.
2Dogs and cats were treated topically with indoxacarb (19.53% w/w; ACTIVYL® Merck Animal Health) accordingly to label directions.
3Dogs were treated topically with fipronil (9.8% w/w)–(s)-methoprene (8.8% w/w) spot-on (Frontline®Plus; Merial) and cats were treated topically with fipronil (9.8% w/w)–(s)-methoprene (11.8% w/w) (Frontline®Plus; Merial) according to label directions.
4Geometric mean numbers of fleas recovered in two intermittent light flea traps.
5{(Day 0 geometric mean trap flea counts – day x geometric mean trap flea counts)/day 0 geometric mean trap flea counts)} x 100
a,bGeometric means in a column with unlike letter superscripts are significantly different (P values ≤0.0054).