Reducing intracellular Cl− concentration decreases the decay time constant of evoked IPSCs. A, Consecutively evoked (gray) and averaged (black) eIPSCs recorded at −100 mV from Purkinje cells in an acute cerebellar slice using: 5, 10, 30, or 150 mm internal Cl− solutions. B, Cumulative distributions for eIPSC decay times measured at −100 mV in Purkinje cells recorded with 5, 10, 30, or 150 mm internal Cl−. C, Bar chart of the decay-time constants for eIPSCs at −100 (n = 13) and 20 mV (n = 6) holding potentials with high (black, 150 mm) or low (gray, 10 mm) internal Cl− concentrations (means ± SEM, *p < 0.05). D, Consecutive (gray) and averaged (black) eIPSCs, recorded with either a 10 or 150 mm internal Cl− solutions at 20 mV.