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. 2014 Jan 15;4:3702. doi: 10.1038/srep03702

Figure 1. dcf1 overexpression caused mitochondrial fission in U251 glioma cell lines.

Figure 1

(a). Co-localization of dcf1 (green) and mitochondria (red) in U251 cells transfected with pEGFP-N2-DCF1. Scale bars, 10000 nm. (b). dcf1 expression leaded to mitochondrial fisson, showing a precursor of cell apoptosis. The mitochondria fissioned in the presence of dcf1 (b1, b2), but remained normal in the cell without transfection of dcf1 (b4). (c). TEM image of swelled mitochondria and almost disappeared cristae(black arrow) in U251 cell overexpressed with DCF1. Scale bars,0.5 μm. (d).AFM image of out membrane appearance change of swelled mitochondrial in U251 cell overexpressed with DCF1. Scale bars, 10000 nm.