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. Author manuscript; available in PMC: 2014 Jan 15.
Published in final edited form as: J Thromb Haemost. 2010 Mar 23;8(6):1431–1433. doi: 10.1111/j.1538-7836.2010.03869.x

Figure 1.

Figure 1

Panel A shows VWF levels for the H1786D proband and family members. VWF:Ag, VWF:RCo, and VWF:CB listed for each subject were performed in the clinical laboratory along with blood type and multimer analysis. The VWF:CB used type III collagen. In addition, plasma samples from the proband and sibling were tested in the research laboratory using collagen binding assays for type I and type III collagen. Results are the mean of 3 separate assays. Panel B shows collagen binding for the recombinant VWF constructs. Binding to type I collagen is shown in black and binding to type III collagen is shown in grey for wild-type (WT), 1731T, 1786D, 1745C, and 1783A VWF. Error bars represent 1 SD for a minimum of 3 separate assays.