Endogenous agonists (pKi) |
beta-defensin 4A (DEFB4A, DEFB4B, O15263) (Selective) 625, CCL20 (pIC50 7.9 – 8.5) 564,565,606
|
CCL21 (Selective) (pIC50 9.3) 627, CCL19 (Selective) (pIC50 7.7 – 9.0) 626,627
|
CCL8 (Mouse), CCL1 (Selective) (pIC50 8.5 – 9.8) 574,585,590
|
CCL25 (Selective) |
CCL27 (Selective), CCL28 (Selective) |
Radioligands (Kd) |
[125I]CCL20 (Agonist, Full agonist) (∼1x10-10 M) 582
|
[125I]CCL19 (Agonist, Full agonist), [125I]CCL21 (Agonist, Full agonist) |
[125I]CCL1 (human) (Agonist, Full agonist) (2.13x10-10 – 1.2x10-9 M) 590,608
|
[125I]CCL25 (Agonist, Full agonist) |
– |