| Nomenclature | CX3CR1 | XCR1 | DARC |
| HGNC, UniProt | CX3CR1, P49238 | XCR1, P46094 | DARC, Q16570 |
| Principal transduction | Gi/o | Gi/o | not defined |
| Endogenous agonists (pKi) | CX3CL1 (Selective) (pIC50 8.9) 578 | XCL1 (Selective), XCL2 (Selective) | – |
| Endogenous ligands | – | – | CXCL5, CXCL6, CXCL8, CXCL11, CCL2, CCL5, CCL7, CCL11, CCL14, CCL17 |
| Selective agonists (pKi) | – | SEAP-XCL1 | – |
| Radioligands (Kd) | [125I]CX3CL1 (human) (Agonist, Full agonist) | – | – |
| Comment | – | When fused with secreted alkaline phophatase (SEAP), XCL1 functions as a probe at XCR1 | – |
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