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. 2013 Dec 17;170(8):1459–1581. doi: 10.1111/bph.12445
Nomenclature GAL1 receptor GAL2 receptor GAL3 receptor
HGNC, UniProt GALR1, P47211 GALR2, O43603 GALR3, O60755
Principal transduction Gi/o Gi/o, Gq/11 Gi/o
Rank order of potency galanin > galanin-like peptide 881 galanin-like peptide ≥ galanin 881 galanin-like peptide > galanin 878
Selective agonists (pKi) [D-Trp2]galanin-(1–29) (8.15 - Rat) 887, galanin(2–29) (rat/mouse) (7.25–8.72 - Rat) 882,891893
Selective antagonists (pKi) 2,3-dihydro-1,4-dithiin-1,1,4,4-tetroxide (pIC50 5.57) 884 M871 (7.88) 889