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. 2013 Dec 17;170(8):1459–1581. doi: 10.1111/bph.12445
Nomenclature NTS1 receptor NTS2 receptor
HGNC, UniProt NTSR1, P30989 NTSR2, O95665
Principal transduction Gq/11 Gq/11
Rank order of potency neurotensin > neuromedin N 1332 neurotensin = neuromedin N 1335
Selective agonists (pKi) JMV449 1338 levocabastine (6.8) 1335,1337
Selective antagonists (pKi) SR48692 (pIC50 7.5–8.2) 1331
Radioligands (Kd) [3H]SR48692 (Antagonist) (3.2x10−9 M – Rat) 1333