| Nomenclature | HGNC, UniProt | Principal transduction | Rank order of potency | Endogenous agonists (pKi) | Radioligands (Kd) |
| apelin receptor | APLNR, P35414 | Gi/o | [Pyr1]apelin-13 ≥ apelin-13 > apelin-36 443,450 | apelin-13 (Selective) (pIC50 8.8 – 9.5) 443,444,448, apelin-17 (Selective) (pIC50 7.9 – 9.02) 442,448, apelin-36 (Selective) (pIC50 8.2 – 8.6) 443,444,446,448, [Pyr1]apelin-13 (Selective) (pIC50 7.0 – 8.8) 446,448 | [125I][Nle75,Tyr77]apelin-36 (human) (Agonist, Full agonist) (6.3x10-12 M) 446, [125I][Glp65Nle75,Tyr77]apelin-13 (Agonist, Full agonist) (2.23x10-11 M) 444, [125I](Pyr1)apelin-13 (Agonist, Full agonist) (3x10-10 M) 445, [125I]apelin-13 (Agonist, Full agonist) (7x10-10 M) 443, [3H](Pyr1)[Met(0)11]-apelin-13 (Agonist, Full agonist) (2.7x10-9 M) 448 |
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