Skip to main content
. 2013 Dec 17;170(8):1607–1651. doi: 10.1111/bph.12447
Nomenclature K2P1.1, K2P6.1, K2P7.1 K2P2.1, K2P10.1, K2P4.1 K2P3.1, K2P9.1, K2P15.1 K2P16.1, K2P5.1, K2P17.1 K2P13.1, K2P12.1 K2P18.1
HGNC, UniProt KCNK1, O00180; KCNK6, Q9Y257; KCNK7, Q9Y2U2 KCNK2, O95069; KCNK10, P57789; KCNK4, Q9NYG8 KCNK3, O14649; KCNK9, Q9NPC2; KCNK15, Q9H427 KCNK16, Q96T55; KCNK5, O95279; KCNK17, Q96T54 KCNK13, Q9HB14; KCNK12, Q9HB15 KCNK18, Q7Z418
Endogenous activators (EC50) arachidonic acid
Activators (EC50) halothane, riluzole halothane
Inhibitors anandamide, ruthenium red halothane
Endogenous inhibitors arachidonic acid
Functional characteristics Background current Background current Background current Background current Background current Background current
Comment K2P1.1 is inhibited by acid pHi, K2P6.1 is inhibited by acid pHi, K2P7.1 is inhibited by acid pHi K2P2.1 is also activated by stretch, heat and acid pHi, K2P10.1 is also activated by stretch, heat and acid pHi, K2P4.1 is also activated by stretch, heat and acid pHi K2P3.1 is also activated by alkakine pHo and inhibited by acid pHo, K2P9.1 is also inhibited by acid pHo, K2P15.1 is inhibited by acid pHo K2P16.1 is activated by alkaline pHo, K2P5.1 is activated by alkaline pHo, K2P17.1 is activated by alkaline pHo