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. 2013 Dec 17;170(8):1706–1796. doi: 10.1111/bph.12450
Nomenclature CHT
Systematic nomenclature SLC5A7
Common abbreviation CHT
HGNC, UniProt SLC5A7, Q9GZV3
Endogenous substrates choline
Substrates triethylcholine
Selective inhibitors (pIC50) hemicholinium-3 (pKi 8.3 – 9.0)
Radioligands (Kd) [3H]hemicholinium-3 (4x10-9 – 6x10-9 M)
Stoichiometry Na+: choline (variable stoichimetry); modulated by extracellular Cl-128