Skip to main content
. 2013 Dec 17;170(8):1706–1796. doi: 10.1111/bph.12450
Nomenclature B0AT1 B0AT2 B0AT3 NTT5 NTT4 SIT1
Systematic nomenclature SLC6A19 SLC6A15 SLC6A18 SLC6A16 SLC6A17 SLC6A20
HGNC, UniProt SLC6A19, Q695T7 SLC6A15, Q9H2J7 SLC6A18, Q96N87 SLC6A16, Q9GZN6 SLC6A17, Q9H1V8 SLC6A20, Q9NP91
Endogenous substrates L-leucine, L-methionine, L-isoleucine, L-valine > L-asparagine, L-phenylalanine, L-alanine, L-serine > L-threonine, glycine, L-proline 152 L-proline > L-alanine, L-valine, L-methionine, L-leucine > L-isoleucine, L-threonine, L-asparagine, L-serine, L-phenylalanine > glycine 152 L-alanine, glycine > L-methionine, L-phenylalanine, L-leucine, L-histidine, L-glutamine 203 L-leucine, L-methionine, L-proline > L-cysteine, L-alanine, L-glutamine, L-serine > L-histidine, glycine 209 L-proline
Stoichiometry 1 Na+: 1 amino acid 154 1 Na+: 1 amino acid 151 Na+- and Cl- -dependent transport 193 Na+-dependent, Cl--independent transport 209 2 Na+: 1 Cl-: 1 imino acid 150
Comment Mutations in B0AT1 are associated with Hartnup disorder