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. 2013 Dec 17;170(8):1797–1867. doi: 10.1111/bph.12451
Nomenclature Cystathionine β-synthase Cystathionine γ-lyase L-Cysteine:2-oxoglutarate aminotransferase 3-Mercaptopyruvate sulfurtransferase
Common abbreviation CBS CSE CAT MPST
HGNC, UniProt CBS, P35520 CTH, P32929 CCBL1, Q16773 MPST, P25325
EC number 4.2.1.22 4.4.1.1 4.4.1.13 2.8.1.2
Endogenous substrates L-homocysteine, L-cysteine (Km 6x10-3 M) 269 L-cysteine L-cysteine 3-mercaptopyruvic acid (Km 1.2x10-3 M) 270
Products cystathionine NH3, pyruvic acid NH3, pyruvic acid pyruvic acid
Cofactors pyridoxal phosphate pyridoxal phosphate pyridoxal phosphate Zn2+
Inhibitors (pIC50) aminooxyacetic acid propargylglycine