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. 2013 Dec 17;170(8):1797–1867. doi: 10.1111/bph.12451
Nomenclature Caspase 9 Caspase 10 Caspase 14
HGNC, UniProt CASP9, P55211 CASP10, Q92851 CASP14, P31944
EC number 3.4.22.62 3.4.22.63 3.4.22.-
Endogenous activators DISC
Endogenous substrates caspase 9, PARP, pro-caspase 3, pro-caspase 6, pro-caspase 7 caspase 10, pro-caspase 3, pro-caspase 6, pro-caspase 7
Selective inhibitors (pIC50) Z-LEHD-FMK 298
Comment Consists of caspase-9 subunit p35 and caspase-9 subunit p10 (see Uniprot entry) Consists of caspase-10 subunit p23/17 and caspase-10 subunit p12 (see Uniprot entry) Consists of caspase-14 subunit p19 and caspase-14 subunit p10 (see Uniprot entry)