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. 2013 Dec 17;170(8):1797–1867. doi: 10.1111/bph.12451
Nomenclature Common abbreviation HGNC, UniProt EC number Comment
dystrophia myotonica-protein kinase DMPK1 DMPK, Q09013 2.7.11.1 Reduced expression of DMPK is associated with myotonic dystrophy 1 336
CDC42 binding protein kinase gamma (DMPK-like) DMPK2 CDC42BPG, Q6DT37 2.7.11.1
CDC42 binding protein kinase alpha (DMPK-like) MRCKα CDC42BPA, Q5VT25 2.7.11.1 Reported to have a role in cellular iron regulation 317
CDC42 binding protein kinase beta (DMPK-like) MRCKβ CDC42BPB, Q9Y5S2 2.7.11.1 Reported to be involved in cell migration 332
citron (rho-interacting, serine/threonine kinase 21) CRIK CIT, O14578 2.7.11.1 Shares structural homology with the Rho kinases
Microtubule associated serine/threonine kinase 1 MAST1 MAST1, Q9Y2H9 2.7.11.1 Members of the microtubule-associated serine/threonine kinase family appear to have a role in platelet production 335 and inflammatory bowel disease 340
Microtubule associated serine/threonine kinase 2 MAST2 MAST2, Q6P0Q8 2.7.11.1 See comment for MAST1
Microtubule associated serine/threonine kinase 3 MAST3 MAST3, O60307 2.7.11.1 See comment for MAST1
Microtubule associated serine/threonine kinase 4 MAST4 MAST4, O15021 2.7.11.1 See comment for MAST1
Microtubule associated serine/threonine kinase-like MASTL MASTL, Q96GX5 2.7.11.1 See comment for MAST1
large tumor suppressor kinase 1 LATS1 LATS1, O95835 2.7.11.1 The large tumour suppressor protein kinases are phosphorylated and activated by MST2 kinase (serine/threonine kinase 3, STK3, Q13188, 314)
large tumor suppressor kinase 2 LATS2 LATS2, Q9NRM7 2.7.11.1 See comment for LATS1
Serine/threonine kinase 38 NDR1 STK38, Q15208 2.7.11.1
Serine/threonine kinase 38 like NDR2 STK38L, Q9Y2H1 2.7.11.1
3-phosphoinositide dependent protein kinase-1 PDK1 PDPK1, O15530 2.7.11.1
protein kinase N1 PKN1 PKN1, Q16512 2.7.11.13 PKN family members are activated by Rho, PIP3 and PDK1 321
protein kinase N2 PKN2 PKN2, Q16513 2.7.11.13 See comment for PKN1
protein kinase N3 PKN3 PKN3, Q6P5Z2 2.7.11.13 See comment for PKN1
ribosomal protein S6 kinase, 90kDa, polypeptide 5 MSK1 RPS6KA5, O75582 2.7.11.1 The mitogen- and stress-acted protein kinases are activated by phosphorylation evoked by MAP kinases and appear to be central to that pathway of cAMP response element-binding protein phosphorylation 352
ribosomal protein S6 kinase, 90kDa, polypeptide 4 MSK2 RPS6KA4, O75676 2.7.11.1 See comment for MSK1
ribosomal protein S6 kinase, 70kDa, polypeptide 1 p70S6K RPS6KB1, P23443 2.7.11.1 Ribosomal S6 kinases 70 kDa, also known as p70rsk, are activated by MAP kinase-mediated phosphorylation
ribosomal protein S6 kinase, 70kDa, polypeptide 2 p70S6Kβ RPS6KB2, Q9UBS0 2.7.11.1 See comment for p70S6K
ribosomal protein S6 kinase, 90kDa, polypeptide 1 p90RSK RPS6KA1, Q15418 2.7.11.1 Ribosomal S6 kinase 90 kDa serine/threonine kinases, also known as p90rsk or MAPK-activated protein kinase-1 (MAPKAP-K1), are activated by MAP kinase -mediated phosphorylation. RSK protein kinases are also activated by phosphorylation by TORC1 327,338 and PDK1 333. Substrates include ribosomal S6 protein (RPS6, P62753), GS3β (P49841) 349) and the 5HT2A receptor 348
ribosomal protein S6 kinase, 90kDa, polypeptide 3 RSK2 RPS6KA3, P51812 2.7.11.1 see comment for p90RSK
ribosomal protein S6 kinase, 90kDa, polypeptide 2 RSK3 RPS6KA2, Q15349 2.7.11.1 see comment for p90RSK
ribosomal protein S6 kinase, 90kDa, polypeptide 6 RSK4 RPS6KA6, Q9UK32 2.7.11.1 see comment for p90RSK
SGK494 SGK494, Q96LW2 2.7.11.1 see comment for p90RSK
ribosomal protein S6 kinase, 52kDa, polypeptide 1 RSKL1 RPS6KC1, Q96S38 2.7.11.1
ribosomal protein S6 kinase-like 1 RSKL2 RPS6KL1, Q9Y6S9 2.7.11.1
serum/glucocorticoid regulated kinase 1 SGK1 SGK1, O00141 2.7.11.1 Serum- and glucocorticoid-inducible kinases are regulated at the transcriptional level by serum and glucocorticoids. SGK1 has been reported to be phosphorylated and activated by mouse TORC2 (Q3U182) 326
serum/glucocorticoid regulated kinase 2 SGK2 SGK2, Q9HBY8 2.7.11.1 see comment for SGK1
serum/glucocorticoid regulated kinase family, member 3 SGK3 SGK3, Q96BR1 2.7.11.1 see comment for SGK1
serine/threonine kinase 32A YANK1 STK32A, Q8WU08 2.7.11.1
serine/threonine kinase 32B YANK2 STK32B, Q9NY57 2.7.11.1
serine/threonine kinase 32C YANK3 STK32C, Q86UX6 2.7.11.1