Nomenclature	Pyruvate carboxylase	Acetyl-CoA carboxylase 1	Acetyl-CoA carboxylase 2	Propionyl-CoA carboxylase	γ-Glutamyl carboxylase
Common abbreviation	PC	ACC1	ACC2	–	GGCX
HGNC, UniProt	PC, P11498	ACACA, Q13085	ACACB, O00763	–	GGCX, P38435
Subunits	–	–	–	Propionyl-CoA carboxylase α subunit, Propionyl-CoA carboxylase β subunit	–
EC number	6.4.1.1	6.4.1.2	6.4.1.2	6.4.1.3	4.1.1.90
Endogenous substrates	ATP, pyruvic acid	ATP, acetyl CoA	ATP, acetyl CoA	ATP, propionyl-CoA	glutamyl peptides
Products	ADP, oxalacetic acid, PO34-	malonyl-CoA, ADP, PO34-	malonyl-CoA, ADP, PO34-	ADP, methylmalonyl-CoA, PO34-	carboxyglutamyl peptides
Cofactors	biotin	biotin	biotin	biotin	NADPH, vitamin K hydroquinone
Selective inhibitors (pIC50)	–	TOFA 38	TOFA 38	–	–
Comment	–	Citrate and other dicarboxylic acids are allosteric activators of acetyl-CoA carboxylase	Citrate and other dicarboxylic acids are allosteric activators of acetyl-CoA carboxylase	Propionyl-CoA carboxylase is able to function in both forward and reverse activity modes, as a ligase (carboxylase) or lyase (decarboxylase), respectively	Loss-of-function mutations in γ-glutamyl carboxylase are associated with clotting disorders