| Nomenclature | Common abbreviation | HGNC, UniProt | EC number | Endogenous substrates | Products | Cofactors | Selective inhibitors (pIC50) | Comment |
| L-Aromatic amino-acid decarboxylase | AADC | DDC, P20711 | 4.1.1.28: L-DOPA -> dopamine + CO2 | L-tryptophan, L-DOPA, 5-hydroxy-L-tryptophan | 5-HT, dopamine | pyridoxal phosphate | 3-hydroxybenzylhydrazine, benserazide, carbidopa, L-α-methyldopa | AADC is a homodimer, Reaction 1: L-DOPA -> dopamine + CO2, Reaction 2: 5-hydroxy-L-tryptophan -> 5-HT + CO2, Reaction 3: L-tryptophan -> tryptamine + CO2 |
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