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. 2013 Dec 17;170(8):1797–1867. doi: 10.1111/bph.12451
Nomenclature acetylcholinesterase butyrylcholinesterase
Common abbreviation AChE BChE
HGNC, UniProt ACHE, P22303 BCHE, P06276
EC number 3.1.1.7: acetylcholine + H2O = acetic acid + choline + H+ 3.1.1.7: acetylcholine + H2O = acetic acid + choline + H+
(Sub)family-selective inhibitors (pIC50) physostigmine (7.6 – 7.8) 6 physostigmine (7.6 – 7.8) 6
Selective inhibitors (pIC50) donepezil (7.7 – 8.1) 4,6, BW284C51 (7.7) 5 bambuterol (8.5) 5, rivastigmine (7.4) 6