Nomenclature | acetylcholinesterase | butyrylcholinesterase |
Common abbreviation | AChE | BChE |
HGNC, UniProt | ACHE, P22303 | BCHE, P06276 |
EC number | 3.1.1.7: acetylcholine + H2O = acetic acid + choline + H+ | 3.1.1.7: acetylcholine + H2O = acetic acid + choline + H+ |
(Sub)family-selective inhibitors (pIC50) | physostigmine (7.6 – 7.8) 6 | physostigmine (7.6 – 7.8) 6 |
Selective inhibitors (pIC50) | donepezil (7.7 – 8.1) 4,6, BW284C51 (7.7) 5 | bambuterol (8.5) 5, rivastigmine (7.4) 6 |