Nomenclature | serine palmitoyltransferase, long chain base subunit 1 | serine palmitoyltransferase, long chain base subunit 2 | serine palmitoyltransferase, long chain base subunit 3 | serine palmitoyltransferase, small subunit A | serine palmitoyltransferase, small subunit B |
Common abbreviation | SPT1 | SPT2 | SPT3 | SPTSSA | SPTSSB |
HGNC, UniProt | SPTLC1, O15269 | SPTLC2, O15270 | SPTLC3, Q9NUV7 | SPTSSA, Q969W0 | SPTSSB, Q8NFR3 |
EC number | 2.3.1.50: palmitoylCoA + L-serine -> 3-Ketosphinganine + coenzyme A + CO2 | – | – | ||
Cofactors | pyridoxal phosphate | pyridoxal phosphate | pyridoxal phosphate | – | – |
Selective inhibitors (pIC50) | myriocin 67 | myriocin 67 | myriocin 67 | – | – |