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. 2013 Dec 17;170(8):1797–1867. doi: 10.1111/bph.12451
Nomenclature serine palmitoyltransferase, long chain base subunit 1 serine palmitoyltransferase, long chain base subunit 2 serine palmitoyltransferase, long chain base subunit 3 serine palmitoyltransferase, small subunit A serine palmitoyltransferase, small subunit B
Common abbreviation SPT1 SPT2 SPT3 SPTSSA SPTSSB
HGNC, UniProt SPTLC1, O15269 SPTLC2, O15270 SPTLC3, Q9NUV7 SPTSSA, Q969W0 SPTSSB, Q8NFR3
EC number 2.3.1.50: palmitoylCoA + L-serine -> 3-Ketosphinganine + coenzyme A + CO2
Cofactors pyridoxal phosphate pyridoxal phosphate pyridoxal phosphate
Selective inhibitors (pIC50) myriocin 67 myriocin 67 myriocin 67