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. 2013 Dec 17;170(8):1797–1867. doi: 10.1111/bph.12451
Nomenclature ceramide synthase 4 ceramide synthase 5 ceramide synthase 6
Common abbreviation CERS4 CERS5 CERS6
HGNC, UniProt CERS4, Q9HA82 CERS5, Q8N5B7 CERS6, Q6ZMG9
EC number 2.3.1.24: sphinganine + acylCoA -> dihydroceramide + coenzyme A, sphingosine + acylCoA -> ceramide + coenzyme A
Substrates C18-, C20- and C22-CoA 72 C16-CoA 64,72 C14- and C16-CoA 68