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. 2013 Dec 17;170(8):1797–1867. doi: 10.1111/bph.12451
Nomenclature PDE5A
HGNC, UniProt PDE5A, O76074
EC number 3.1.4.17
Activators Protein kinase A, protein kinase G 89
Rank order of affinity cGMP > cAMP
Selective inhibitors (pIC50) T0156 (9.5) 117, sildenafil (9.0) 136, gisadenafil (8.9) 122, SCH51866 (7.2) 137, zaprinast (6.8) 136