Nomenclature | Common name | HGNC, UniProt | EC number | Comment |
CYP5A1 | – | TBXAS1, P24557 | 5.3.99.5 | Converts PGH2 to thromboxane A2. Inhibited by dazoxiben 161 and camonagrel 150 |
CYP8A1 | Prostacyclin synthase | PTGIS, Q16647 | 5.3.99.4 | Converts prostaglandin H2 to prostaglandin I2 152. Inhibited by tranylcypromine 149 |
CYP7A1 | – | CYP7A1, P22680 | 1.14.13.17 | Converts cholesterol to 7α-hydroxycholesterol 158 |
CYP7B1 | – | CYP7B1, O75881 | 1.14.13.100 | Converts DHEA to 7α-DHEA 162 |
CYP8B1 | – | CYP8B1, Q9UNU6 | 1.14.13.95 | Converts 7α-hydroxycholest-4-en-3-one to 7-alpha,12α-dihydroxycholest-4-en-3-one (in rabbit) 153 in the biosynthesis of bile acids |