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. 2013 Dec 17;170(8):1797–1867. doi: 10.1111/bph.12451
Nomenclature Common name HGNC, UniProt EC number Comment
CYP5A1 TBXAS1, P24557 5.3.99.5 Converts PGH2 to thromboxane A2. Inhibited by dazoxiben 161 and camonagrel 150
CYP8A1 Prostacyclin synthase PTGIS, Q16647 5.3.99.4 Converts prostaglandin H2 to prostaglandin I2152. Inhibited by tranylcypromine 149
CYP7A1 CYP7A1, P22680 1.14.13.17 Converts cholesterol to 7α-hydroxycholesterol 158
CYP7B1 CYP7B1, O75881 1.14.13.100 Converts DHEA to 7α-DHEA 162
CYP8B1 CYP8B1, Q9UNU6 1.14.13.95 Converts 7α-hydroxycholest-4-en-3-one to 7-alpha,12α-dihydroxycholest-4-en-3-one (in rabbit) 153 in the biosynthesis of bile acids