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. 2011 Mar 24;3(1):e3. doi: 10.4081/idr.2011.e3

Table 4. Simulation of positive and negative predictive values of Ziehl-Neelsen staining, culture, and polymerase chain reaction dot-blot assays, according to different tuberculosis prevalence rates.

Simulated prevalence rates Subjects with
HIV
N=74
Subjects without
HIV
N=203
TB
N=40
TB
N=34
TB
N=88
TB
N=115
PPV NPV PPV NPV
5%
 ZN / cuture 100 99 83 100
 ZN / PCR dot-blot 23 99 23 100
PPV NPV PPV NPV
10%
 ZN / cuture 100 99 91 99
 ZN / PCR dot-blot 38 98 39 99
PPV NPV PPV NPV
20%
 ZN / cuture 100 97 96 99
 ZN / PCR dot-blot 58 98 59 98
PPV NPV PPV NPV
30%
 ZN / cuture 100 95 98 98
 ZN / PCR dot-blot 71 93 71 96
PPV NPV PPV NPV
40%
 ZN / cuture 100 93 98 97
 ZN / PCR dot-blot 79 89 79 94
PPV NPV PPV NPV
46%*
 ZN / cuture 99 88 98 96
 ZN / PCR dot-blot 87 82 83 93

PPV, positive predictive value; NPV, negative predictive value.

*

the present study.