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. 2012 Feb 15;4(1):e12. doi: 10.4081/idr.2012.e12

Table 1. Proposed diagnostic criteria for Gianotti-Crosti syndrome.114,115.

A patient is diagnosed as having Gianotti-Crosti syndrome (GCS, or papular acrodermatitis) if:

  1. on at least one occasion or clinical encounter, he/she exhibits all the positive clinical features;

  2. on all occasions or clinical encounters related to the rash, he/she does not exhibit any of the negative clinical features;

  3. none of the differential diagnoses is considered to be more likely than GCS on clinical judgment;

  4. if lesional biopsy is performed, the findings are consistent with GCS.

The positive clinical features are:

  1. monomorphous, flat-topped, pink-brown papules or papulovesicles 1-10mm in diameter;

  2. at least three of the following four sites involved: (1) cheeks, (2) buttocks, (3) extensor surfaces of forearms, and (4) extensor surfaces of legs;

  3. being symmetrical;

  4. lasting for at least ten days.

The negative clinical features are:

  1. extensive truncal lesions;

  2. scaly lesions.

The differential diagnoses are: acrodermatitis enteropathica, erythema infectiosum, erythema multiforme, hand-foot-and-mouth disease, Henoch-Schönlein purpura, Kawasaki disease, lichen planus, papular urticaria, papular purpuric gloves and socks syndrome, and scabies.